New immunotherapy research in Florida shows promise against brain tumors, sepsis
Researchers in Florida are using immunotherapy against two of the toughest medical problems: glioblastoma brain tumors and infections from sepsis and septic shock. Both conditions are deadly and fast-moving. New updates:
- This week, University of Florida Health researchers announced they have found a way to target a molecule that lets glioblastoma cancer tumors grow, migrate and evade the body’s immune system. The immunotherapy treatment shows effectiveness against deadly brain tumor during early tests. Full story here.
- UF researchers are also in the news this week because they are part of a nationwide clinical trial to evaluate whether an anti-cancer medication can be effective against sepsis. Sepsis blunts the immune system in ways similar to some kinds of cancer through the protein PD-1. Nivolumab, an immunotherapy drug approved by the FDA for certain types of lung cancer, blocks PD-1. The clinical trial seeks to determine whether blocking PD-1 can also boost the immune system in patients with severe sepsis or septic shock. Full story here.
Related story, from Florida Trend:
» Cancer care: The limits of immunotherapy
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