December 22, 2014

Cancer Care

Insights: Cancer care in Florida

Breakthroughs, trends and players in the medical field of oncology

Amy Keller | 5/6/2013

Cancer Insight: Staying a Step Ahead

Gatenby and his team use mathematical tools like game theory, which predicts gains and losses in competitive scenarios, to try to figure out ways to outwit cancer. The idea, he says, it not to sit and wait and see how a tumor reacts to a particular treatment, but rather to anticipate what it will do.

One example that has worked with some cancers, Gatenby says, is combining immunotherapy and chemotherapy. In some cases, he says, a drug that boosts the patient's immune system doesn't kill all the cancer cells, but the cells that avoid the body's immune response do so by taking on properties that make them more vulnerable to chemotherapy. In the end, the cancer isn't completely eradicated, Gatenby says, but the approach produces a kind of uneasy stalemate that keeps it in check.

Why Chemo Sometimes Fails

why chemo fails

Cancer cells in a tumor aren't all the same, and the different variations compete with for survival even as the overall tumor grows.

Traditional, massive doses of chemotherapy wipe out all the cells that are sensitive to the drugs. Others, however, adapt in some way.

While surviving cells may be weaker than those the chemo killed, they now have no competition, and can grow freely.

The cancer recurs, but now in a form that doesn't respond to drugs at all.

Tags: Cancer Care

Digital Access

DIRECT DIGITAL ACCESS
Add digital to your current subscription, purchase a single ditgital issue, or start a new subscription to Florida Trend.

TABLE OF CONTENTS
An overview of the features and articles in this month's issue of Florida Trend.

ACCESS THIS ISSUE »

Florida Business News

Florida Trend Video Pick

Terms of Use Privacy Policy  Indian Rocks Beach Post Office Celebrates 100 Years
Terms of Use Privacy Policy  Indian Rocks Beach Post Office Celebrates 100 Years

It cost a penny to mail a postcard when the Indian Rocks Post Office opened 100 years ago in December 1914 on a mainland dirt road leading to a ferry in the “Narrows.” 

Earlier Videos | Viewpoints@FloridaTrend

Ballot Box

How do you feel about the historic decision to remodel US-Cuba relations?

  • Well, it's about time!
  • I'm cautiously optimistic...
  • I'm skeptical about this at best...
  • Not in favor at all: Keep the embargo strong!

See Results

Ballot Box
Subscribe